姓 名：王軻
性 別：男
職 稱：研究員，博士生/碩士生導師
所在系別：作物遺傳育種系
工作單位：中國農業科顺盈作物科學研究所
電 話：010-82105173
電子郵箱🏵：wangke03@caas.cn
◆個人簡歷（學習/訪學/工作簡歷）
2002.09-2006.07： 臨沂大學，生物科學專業👏，理學學士；
2006.09- 2011.07🍒📨： 首都師範大學，遺傳學專業，理學博士🍦；
2011.07-至今：中國農業科顺盈作物科學研究所 研究員👮🏻，博士生導師。
◆研究領域
主要研究方向是小麥遺傳轉化新技術🤶🏽、基因編輯及小麥營養品質改良。
◆榮譽稱號及社會兼職
1. 阿裏巴巴育種人才青年科學家，2022📥；
2. Frontiers in plant science編委，2021。
◆科研項目
1. 利用CRISPR/Cas9創製春小麥單倍體誘導系和優質種質資源材料，2. 寧夏回族自治區科學技術廳重點研發計劃，64萬元🙌🏽🤾🏿，2022-2025，課題主持人🗒。
2. 小麥再生基因TaCB1在遺傳轉化中的功能鑒定及分子機理解析🤵🏿♀️🚊，國家自然科學基金面上項目，58萬元✡︎，2020-2023🪕，課題主持人。
3. 小麥遺傳轉化相關新技術研究，國家轉基因專項，45萬元🪠，2016-2020🗞，子課題主持人
4. 小麥TaVIP2基因的克隆☝🏼、功能鑒定及分子機理研究，國家自然科學基金面上項目，26萬元，2015-2017🙍🏽♀️，課題主持人🏡🫄🏽。
◆授權專利
1. 王軻，劉會雲，葉興國，王坤揚，伍小波，杜麗璞🤜🏿，李婕琳，李欣👩🏽🎨，李仕金。一種表達載體及其在製備轉基因植物中的應用🧙🏼，ZL201610204910.0，國家發明專利，2020。
2. 王軻😖，葉興國，劉會雲🤞🏻，王坤楊，杜麗璞，王靜，林誌珊。小麥TaWOX5基因在提高小麥轉化效率中的應用，ZL201710422896.6，國家發明專利⚉，2020。
3. Ye Xingguo, Wang ke, Ishida Yuji, Yanagihara, Chizu, Liu Huiyun, Wang Kunyang, Shi Lei, Du Lipu, Wang Jing, Lin Zhishan. Method for improving transformation efficiency of plant and method for transforming plant👨🏿🎨，US 11,447,784 B2，美國發明專利，2022🤰🏽🐲。
4. Ye Xingguo, Wang ke, Ishida Yuji, Yanagihara, Chizu, Liu Huiyun, Wang Kunyang, Shi Lei, Du Lipu, Wang Jing, Lin Zhishan. Method for improving transformation efficiency of plant and method for transforming plant，2018280528🦼，澳大利亞發明專利，2022🔻。
◆發表論文
1. Wang K, Shi L, Liang XN, Zhao P, Wang WX, Liu JX, Chang YN, Hiei Y, Yanagihara C, Du LP, Ishida Y, Ye XG. The gene TaWOX5 overcomes genotype dependency in wheat genetic transformation. Nature Plants, 2022, 8:110-117.
2. Cheng JY, Hill C, Yong Han Y, He TH, Ye XG, Shabala S, Guo GG, Zhou MX, Wang K, Li CD, New semi-dwarfing alleles with increased coleoptilelength by gene editing ofgibberellin 3-oxidase 1usingCRISPR-Cas9 in barley (Hordeum vulgare L.). Plant Biotechnology Journal, 2023, 21:806–818.
3. Zhu YW, Lin YR, Fan YJ, Wang YW, Li PF, Xiong J, He YH, Cheng SF, Ye XG, Wang F, Goodrich J, Zhu JK, Wang K, Zhang CJ. CRISPR/Cas9-mediated restoration of Tamyb10 to create pre-harvest sprouting-resistant red wheat, Plant Biotechnology Journal, 2023, 21:665–667 IF2022=13.8
4. Qu G, Wang K, Mu JY, Zhuo JH, Wang XY, Li SS, Ye XG, Li YX, Yan YM, Li XH. Identifying cis-Acting Elements Associated with the High Activity and Endosperm Specificity of the Promoters of Genes Encoding Low-Molecular-Weight Glutenin Subunits in Common Wheat (Triticum aestivum) J. Agric. Food Chem. 2023, 71, 17432−17441.
5. Zhuo JH, Wang K, Wang N, Xing CH, Peng D, Wang XY, Qu G, Kang CY, Ye XG, Li YX, Yan YM, L XH. 330: 111622.
6. Tang HL, Qiu YL, Wang WX, Yu M, Chang YN, Du LP, Lin ZS, Wang K, Ye XG. Development of a haploid inducer by editing HvMTL in barley. Journal of Genetics and Genomics👩🏻✈️，2023, 50: 366-369.
7. Wang WX, Huang PP, Dai WS, Tang HL, Qiu YL, Chang YN, Han ZY, Li X, Du LP, Ye XG, Zou C, Wang K. Application of Nicotinamide to Culture Medium Improves the Efficiency of Genome Editing in Hexaploid Wheat.International Journal of Molecular Sciences, 2023, 24: 4416.
8. Hu JX, Yu M, Chang YN, Tang HL, Wang WX, Du LP, Wang K, Yan YM, Ye XG. Functional analysis of TaPDI genes on storage protein accumulation by CRISPR/Cas9 edited wheat mutants. International Journal of Biological Macromolecules, 2022, 196: 131-143.
9. Zang YM, Gong Q, Xu YH, Liu HY, Bai H, Li N, Du LP, Ye XG, Lan CX, Wang K. Production of conjoined transgenic and edited barley and wheat plants for Nud genes using the CRISPR/SpCas9 System. Frontiers in Genetics, 2022, 13: 873850.
10. Qiu YL, Chen HQ, Zhang SX, Wang J, Du LP, Wang K, Ye XG. Development of a wheat material with improved bread-making quality by overexpressing HMW-GS 1Slx2.3* from Aegilops longissima. The Crop Journal, 2022, 10:1717-1726.
11. Tang HL, Liu HY, Zhou Y, Liu HW, Du LP, Wang K, Ye XG. Fertility recovery of wheat male sterility controlled by Ms2 using CRISPR/Cas9. Plant Biotechnology Journal, 2021, 19: 224–226.
12. Chen HQ, Li SJ, Liu YW, Liu JX, Ma XL, Du LP, Wang K, Ye XG. Effects of 1Dy12 subunit silencing on protein body accumulation in seeds and flour-processing quality in a common wheat somatic variation line. Food Chemistry, 2021, 335: 127663.
13. Liu HY, Wang K, Jia ZM, Gong Q, Lin ZS, Lipu Du LP, Pei XW, Ye XG. Efficient induction of haploid plants in wheat by editing of TaMTL using an optimized Agrobacterium-mediated CRISPR system. Journal of Experimental Botany, 2020, 71:1337–1349.
14. Liu HY, Wang K, Tang HL, Gong Q, Du LP, Pei XW, Ye XG. CRISPR/Cas9 editing of wheat TaQ genes alters spike morphogenesis and grain threshability. Journal of Genetics and Genomics, 2020, 47: 563-575.
15. Liang QJ, Wang K, Sharifula I, Ye XG, Zhang CY. Folate content and retention in wheat grains and wheat-based foods: Effects of storage, processing, and cooking methods. Food Chemistry, 2020, 333: 127459.
16. Wang K, Gong Q, Ye XG. Recent developments and applications of genetic transformation and genome editing technologies in wheat. Theoretical and Applied Genetics, 2020, 133:1603-1622.
17. Riaz B, Chen HQ, Wang J, Du LP, Wang K, Ye XG. Overexpression of Maize ZmC1 and ZmR Transcription Factors in Wheat Regulates Anthocyanin Biosesynthesis in a Tissue-Specific Manner. International Journal of Molecular Sciences, 2019, 20, 5806.
18. Liang QJ, Wang K, Liu XN, Riaz B, Jiang L, Wan X, Ye XG, Zhang CY. Improved folate accumulation in genetically modified maize and wheat. Journal of Experimental Botany, 2019, 70(5): 1539-1551.
19. Wang K, Riaz B, Ye XG. Wheat genome editing expedited by efficient transformation techniques: Progress and perspectives, Crop Journal, 2018, 6(1): 22-31.
Wang K, Liu HY, Du LP, Ye XG. Generation of marker-free transgenic hexaploid wheat via an Agrobacterium-mediated co-transformation strategy in commercial Chinese wheat varieties, Plant Biotechnology Journal, 2017, 15(5): 614-623.
